Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 13/20 | 0.40 |
| ▸ | KLRK1 | P26718 | 4/20 | 0.40 |
| ▸ | MICA | Q29983 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAET1L | Q5VY80 | 3/20 | 0.39 |
| ▸ | APOB | P04114 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069281 | 0.93 | MTTP (0.42) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL5065115 | 0.92 | MTTP (0.41) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL5065140 | 0.89 | MTTP (0.39) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL5069238 | 0.88 | MTTP (0.41) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL5065148 | 0.88 | MTTP (0.44) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL5064980 | 0.86 | MTTP (0.41) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL5069239 | 0.85 | MTTP (0.44) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL5068166 | 0.83 | MTTP (0.41) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL14031701 | 0.83 | MTTP (0.42) | MTTPKLRK1MICAALDH1A1HPGD | |
| SCHEMBL5065222 | 0.82 | MTTP (0.41) | MTTPKLRK1MICARAET1LAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | claimed |
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20060205726-A1 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205726-A1 | Ester derivatives and medical use thereof | MTTP, LIPC, CETP | MTTP 1/4885KLRK1 3940/4885MICA 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.