SCHEMBL5065172

SCHEMBL5065172

CCCCCCCCc1ccc(-c2ccc(C(=O)Oc3ccc(CC(C)CC)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
RARB P10826 7/20 0.53
MEN1 O00255 1/20 0.53
ALDH1A1 P00352 1/20 0.53
RARA P10276 1/20 0.53
MTOR P42345 1/20 0.53
KMT2A Q03164 1/20 0.53
THRB P10828 5/20 0.49
THRA P10827 3/20 0.49
PPARA Q07869 1/20 0.46
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10746703 1.00 MAPT (0.54) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL20594559 1.00 MAPT (0.54) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL20594622 1.00 MAPT (0.54) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL9434739 1.00 MAPT (0.54) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL9185134 1.00 MAPT (0.54) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL29359854 1.00 MAPT (0.54) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL20594587 0.99 MAPT (0.55) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL742165 0.99 MAPT (0.55) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL11547790 0.99 MAPT (0.55) MAPTSMN1; SMN2RARBMEN1ALDH1A1
SCHEMBL20594581 0.96 THRB (0.52) MAPTSMN1; SMN2RARBMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7215491-B2 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-05-08 US claimed
US-20050248844-A1 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2005-11-10 US claimed
EP-1716718-B1 OPTICALLY CONTROLLED OPTICAL-PATH-SWITCHING-TYPE OPTICAL SIGNAL TRANSMISSION APPARATUS, AND METHOD OF SWITCHING OPTICAL PATHS FOR OPTICAL SIGNALS DAINICHISEIKA COLOR CHEM (JP) 2012-10-31 EP disclosed
EP-1726183-B1 OPTICALLY CONTROLLED OPTICAL-PATH-SWITCHING-TYPE DATA DISTRIBUTION APPARATUS AND DISTRIBUTION METHOD DAINICHISEIKA COLOR CHEM (JP) 2012-10-24 EP disclosed
US-20080106689-A1 Display Element And Display Device INOUE IICHIRO 2008-05-08 US disclosed
US-20070159682-A1 Optically controlled optical-path-switching-type data distribution apparatus and distribution method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-07-12 US disclosed
US-7215491-B2 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-05-08 US disclosed
US-20050248844-A1 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2005-11-10 US disclosed
EP-0840145-B1 POLARIZATION CONVERTER, OPTICAL CONVERTER, ELECTRONIC APPARATUS AND PROCESS FOR PRODUCING POLARIZATION CONVERTER SEIKO EPSON CORP (JP) 2005-04-27 EP disclosed
US-6624859-B1 Apparatus comprising optically active material which exhibits anisotropy with respect to optical activity, and increases intensity of luminous flux having particular plane of polarization and reduces that having perpendicular plane SEIKO EPSON CORPORATION (JP) 2003-09-23 US disclosed
US-5279764-A Dihalogenobenzene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-18 US disclosed
EP-0511845-A1 Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles RHONE-POULENC AGROCHIMIE (FR) 1992-11-04 EP disclosed
US-5064566-A Chirally tilted, pyrimidines, pyridines, or pyrazines, stability MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-12 US disclosed
EP-0175591-B1 LACTIC ACID DERIVATIVE, LIQUID CRYSTAL COMPOSITION CONTAINING SAME AND LIQUID CRYSTAL DEVICE CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
US-4979805-A Ferroelectric liquid crystal device containing optically active azo or azoxy benzene type mesomorphic compound with extended life CANON KABUSHIKI KAISHA (JP) 1990-12-25 US disclosed
EP-0373186-A1 DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE MERCK PATENT GmbH (DE) 1990-06-20 EP disclosed
WO-1989008637-A1 DERIVATIVES OF 2,3-DIFLUOROHYDROQUINONE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
EP-0332007-A1 Derivatives of 2,3-difluorohydroquinone MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
US-4775223-A DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 1988-10-04 US disclosed
EP-0175591-A2 Lactic acid derivative, liquid crystal composition containing same and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1986-03-26 EP disclosed