SCHEMBL5065175

SCHEMBL5065175

CCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2)c(-c2ccc(CC(C)CC)cc2)c1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RARB P10826 12/20 0.59
RARA P10276 2/20 0.59
MEN1 O00255 1/20 0.59
ALDH1A1 P00352 1/20 0.59
MAPT P10636 1/20 0.59
MTOR P42345 1/20 0.59
KMT2A Q03164 1/20 0.59
NPC1 O15118 1/20 0.48
NFKB1 P19838 1/20 0.48
RAB9A P51151 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MPL P40238 1/20 0.47
PTPN11 Q06124 1/20 0.46
KAT8 Q9H7Z6 2/20 0.44
PPARA Q07869 1/20 0.44
RARG P13631 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5065174 0.93 RARB (0.65) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL8839108 0.90 RARB (0.61) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL11219236 0.88 FOLH1 (0.46) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL11225323 0.87 RARB (0.58) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL9145967 0.86 RARB (0.49) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL20594584 0.86 PPARA (0.55) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL8839087 0.85 RARB (0.61) RARBPTPN11
SCHEMBL10435818 0.85 RARB (0.61) RARBPTPN11
SCHEMBL6233140 0.85 PTPN11 (0.64) RARBPTPN11
SCHEMBL11219231 0.84 MEN1 (0.47) RARBMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080106689-A1 Display Element And Display Device INOUE IICHIRO 2008-05-08 US disclosed
EP-0840145-B1 POLARIZATION CONVERTER, OPTICAL CONVERTER, ELECTRONIC APPARATUS AND PROCESS FOR PRODUCING POLARIZATION CONVERTER SEIKO EPSON CORP (JP) 2005-04-27 EP disclosed
US-6624859-B1 Apparatus comprising optically active material which exhibits anisotropy with respect to optical activity, and increases intensity of luminous flux having particular plane of polarization and reduces that having perpendicular plane SEIKO EPSON CORPORATION (JP) 2003-09-23 US disclosed