SCHEMBL5065174

SCHEMBL5065174

CCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2-c2ccc(CC(C)CC)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 12/20 0.65
RARA P10276 2/20 0.59
MEN1 O00255 1/20 0.59
ALDH1A1 P00352 1/20 0.59
MAPT P10636 1/20 0.59
MTOR P42345 1/20 0.59
KMT2A Q03164 1/20 0.59
MPL P40238 1/20 0.47
RARG P13631 1/20 0.46
PTPN11 Q06124 1/20 0.46
NPC1 O15118 1/20 0.46
NFKB1 P19838 1/20 0.46
RAB9A P51151 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PLA2G1B P04054 2/20 0.43
ATG4B Q9Y4P1 2/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5065175 0.93 RARB (0.59) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL10774091 0.91 RARB (0.65) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL11219231 0.89 MEN1 (0.47) RARBMEN1ALDH1A1MAPTKMT2A
SCHEMBL10773978 0.88 PTPN11 (0.59) RARBPTPN11
SCHEMBL6233137 0.88 PTPN11 (0.59) RARBPTPN11
SCHEMBL10435819 0.88 PTPN11 (0.59) RARBPTPN11
SCHEMBL8839108 0.85 RARB (0.61) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL6233140 0.85 PTPN11 (0.64) RARBPTPN11
SCHEMBL9507964 0.84 RARB (0.73) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL10490937 0.84 RARB (0.72) RARBRARAMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080106689-A1 Display Element And Display Device INOUE IICHIRO 2008-05-08 US disclosed
EP-0840145-B1 POLARIZATION CONVERTER, OPTICAL CONVERTER, ELECTRONIC APPARATUS AND PROCESS FOR PRODUCING POLARIZATION CONVERTER SEIKO EPSON CORP (JP) 2005-04-27 EP disclosed
US-6624859-B1 Apparatus comprising optically active material which exhibits anisotropy with respect to optical activity, and increases intensity of luminous flux having particular plane of polarization and reduces that having perpendicular plane SEIKO EPSON CORPORATION (JP) 2003-09-23 US disclosed