Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.89 |
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.89 |
| ▸ | LMNA | P02545 | 2/20 | 0.89 |
| ▸ | TSHR | P16473 | 2/20 | 0.89 |
| ▸ | BLM | P54132 | 2/20 | 0.89 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.89 |
| ▸ | MEN1 | O00255 | 2/20 | 0.89 |
| ▸ | MPO | P05164 | 1/20 | 0.89 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.89 |
| ▸ | APAF1 | O14727 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | HTR7 | P34969 | 2/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL5065251 | 1.00 | KDM4E (0.89) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL6033338 | 0.95 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL9481720 | 0.95 | KDM4E (0.84) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27748750 | 0.94 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28580277 | 0.94 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL27748748 | 0.94 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL23141133 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL4732052 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL289042 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL19161120 | 0.94 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106636044-B | Nitrilase mutant and coding gene and application thereof | 东莞东阳光药物研发有限公司 | 2019-10-18 | — | — | CN | disclosed |
| US-8809494-B2 | Method and compositions for prevention and treatment of malaria infections | DREXEL UNIVERSITY (US) | 2014-08-19 | — | — | US | disclosed |
| US-20080274113-A1 | Method and Compositions for Prevention and Treatment of Malaria Infections | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-11-06 | — | — | US | disclosed |
| US-4568545-A | ANTICOAGULANTS, EARTHWORM TISSUE EXTRACTS | AMANO SEIYAKU KABUSHIKI KAISHA (JP) | 1986-02-04 | — | — | US | disclosed |