Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 11/20 | 0.69 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.69 |
| ▸ | RXRA | P19793 | 9/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678610 | 0.86 | NR1H2 (0.72) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL5062337 | 0.83 | NR1H2 (0.49) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL5268643 | 0.83 | NR1H2 (0.74) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1679291 | 0.83 | NR1H2 (0.78) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1679093 | 0.81 | NR1H2 (0.82) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1678331 | 0.81 | NR1H2 (1.00) | NR1H2NR1H3RXRA | |
| SCHEMBL1679564 | 0.81 | NR1H2 (0.64) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL5267508 | 0.80 | NR1H2 (0.71) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1678811 | 0.80 | NR1H2 (0.67) | NR1H2NR1H3RXRAMAOBMAOA | |
| SCHEMBL1678343 | 0.79 | NR1H2 (0.72) | NR1H2NR1H3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | NR1H2 7/4885NR1H3 6/4885RXRA 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.