Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068961 | 0.93 | PIM1 (0.52) | PIM1AKT2HCAR2SIRT2EGFR | |
| SCHEMBL810939 | 0.93 | PIM1 (0.54) | PIM1AKT2EGFRMEN1MAPT | |
| SCHEMBL4976018 | 0.90 | PIM1 (0.54) | PIM1AKT2SIRT2EGFRABCG2 | |
| SCHEMBL5061334 | 0.88 | PIM1 (0.66) | PIM1AKT2HCAR2SIRT2EGFR | |
| SCHEMBL5067844 | 0.87 | PIM1 (0.55) | PIM1AKT2SIRT2EGFRABCG2 | |
| SCHEMBL810273 | 0.85 | PIM1 (0.60) | PIM1AKT2EGFRMEN1MAPT | |
| SCHEMBL810618 | 0.84 | PIM1 (0.57) | PIM1AKT2EGFRABCG2MEN1 | |
| SCHEMBL810912 | 0.83 | PIM1 (0.58) | PIM1AKT2EGFRMEN1MAPT | |
| SCHEMBL810060 | 0.83 | PIM1 (0.58) | PIM1AKT2EGFRABCG2MEN1 | |
| SCHEMBL810397 | 0.82 | PIM1 (0.55) | PIM1AKT2EGFRABCG2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |