Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | AKT2 | P31751 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 8/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810912 | 0.93 | PIM1 (0.58) | PIM1AKT2EGFRERBB2HDAC3 | |
| SCHEMBL5067844 | 0.92 | PIM1 (0.55) | PIM1AKT2EGFRSIRT2FBP1 | |
| SCHEMBL5065655 | 0.90 | PIM1 (0.50) | PIM1AKT2EGFRSIRT2ERBB2 | |
| SCHEMBL5065555 | 0.88 | PIM1 (0.70) | PIM1AKT2EGFRSIRT2FBP1 | |
| SCHEMBL5068961 | 0.88 | PIM1 (0.52) | PIM1AKT2EGFRSIRT2ABCG2 | |
| SCHEMBL5067752 | 0.86 | PIM1 (0.57) | PIM1AKT2EGFRFBP1 | |
| SCHEMBL811361 | 0.86 | PIM1 (0.59) | PIM1AKT2EGFRERBB2HDAC3 | |
| SCHEMBL810273 | 0.85 | PIM1 (0.60) | PIM1AKT2EGFRERBB2HDAC6 | |
| SCHEMBL810543 | 0.83 | PIM1 (0.56) | PIM1AKT2EGFRERBB2HDAC3 | |
| SCHEMBL810939 | 0.83 | PIM1 (0.54) | PIM1AKT2EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |