Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | IL6ST | P40189 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 8/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153769 | 1.00 | PPARA (0.49) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL5065686 | 1.00 | PPARA (0.49) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL15873519 | 0.90 | PPARA (0.48) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21113600 | 0.90 | PPARA (0.48) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL9554132 | 0.90 | PPARA (0.48) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL24418522 | 0.90 | IL6ST (0.52) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL7406075 | 0.88 | PPARA (0.47) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL2206996 | 0.88 | PPARA (0.47) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL13316517 | 0.88 | PPARA (0.54) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL14314072 | 0.88 | PPARA (0.54) | PPARAIL6STNAAAIDH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10611739-B2 | Process for preparation of lactone derivatives and intermediates thereof | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2020-04-07 | — | — | US | disclosed |
| US-20190210981-A1 | PROCESS FOR PREPARATION OF LACTONE DERIVATIVES AND INTERMEDIATES THEREOF | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
| US-20080318838-A1 | PEPTIDES | BAUER WILFRIED | 2008-12-25 | — | — | US | disclosed |
| US-20050009147-A1 | Peptides | BAUER WILFRIED (CH) | 2005-01-13 | — | — | US | disclosed |
| EP-0672057-A1 | ANALOGS OF PTH | Novartis AG (CH) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994002510-A2 | ANALOGS OF PTH | SANDOZ LTD. (CH) | 1994-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10611739-B2 | Process for preparation of lactone derivatives and intermediates thereof | LSS, CYP3A4, HCCS | PPARA 1136/4885IL6ST 2061/4885NAAA 2781/4885 |
| US-20080318838-A1 | PEPTIDES | PTMS, PTH1R, CALCRL | PPARA 1853/4885IL6ST 575/4885NAAA 602/4885 |
| US-20190210981-A1 | PROCESS FOR PREPARATION OF LACTONE DERIVATIVES AND INTERMEDIATES THEREOF | LSS, CYP3A4, HCCS | PPARA 1136/4885IL6ST 2061/4885NAAA 2781/4885 |
| US-20050009147-A1 | Peptides | PTMS, PTH1R, CALCRL | PPARA 1853/4885IL6ST 575/4885NAAA 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.