Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | IL6ST | P40189 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 8/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13438561 | 0.90 | PPARA (0.49) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL5065685 | 0.90 | PPARA (0.49) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21153769 | 0.90 | PPARA (0.49) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL5065686 | 0.90 | PPARA (0.49) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL14503309 | 0.89 | PPARA (0.58) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL12976073 | 0.88 | PPARA (0.47) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL12268098 | 0.88 | PPARA (0.51) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL24418522 | 0.87 | IL6ST (0.52) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL21113600 | 0.87 | PPARA (0.48) | PPARAIL6STNAAAIDH1FAAH | |
| SCHEMBL15873519 | 0.87 | PPARA (0.48) | PPARAIL6STNAAAIDH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5231179-A | Heterocyclic compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0232786-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0232786-A1 | Heterocyclic compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-08-19 | — | — | EP | disclosed |