Methane

Methane

SCHEMBL5065725

C.Oc1c[nH]c2ccccc12

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
CYP3A4 P08684 3/20 0.56
GPR84 Q9NQS5 2/20 0.56
MAPT P10636 2/20 0.56
AHR P35869 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ATM Q13315 2/20 0.52
ALDH1A1 P00352 3/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2A6 P11509 2/20 0.48
MPO P05164 1/20 0.48
CYP1A2 P05177 1/20 0.48
NFKB1 P19838 1/20 0.48
HTR1D P28221 1/20 0.48
HTR1B P28222 1/20 0.48
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48
HTR7 P34969 1/20 0.48
CTSK P43235 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29567690 0.98 MEN1 (0.58) MEN1KMT2ACYP3A4GPR84MAPT
SCHEMBL155191 0.98 MEN1 (0.58) MEN1KMT2ACYP3A4GPR84MAPT
SCHEMBL10550137 0.95 MEN1 (0.56) MEN1KMT2ACYP3A4GPR84MAPT
SCHEMBL27702719 0.95 MEN1 (0.56) MEN1KMT2ACYP3A4GPR84MAPT
SCHEMBL28624457 0.95 MEN1 (0.56) MEN1KMT2ACYP3A4GPR84MAPT
Water SCHEMBL27616945 0.95 MEN1 (0.56) MEN1KMT2ACYP3A4GPR84MAPT
Hydrochloric Acid SCHEMBL28628671 0.95 MEN1 (0.56) MEN1KMT2ACYP3A4GPR84MAPT
SCHEMBL4855690 0.95 MEN1 (0.56) MEN1KMT2ACYP3A4GPR84MAPT
SCHEMBL27714884 0.93 MEN1 (0.54) MEN1KMT2ACYP3A4GPR84MAPT
Potassium Ion SCHEMBL8890535 0.93 MEN1 (0.54) MEN1KMT2ACYP3A4GPR84MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1794986-A Novel methods for the treatment of cancer LANKENAU INST MEDICAL RES (US) 2006-06-28 CN claimed
CN-112118855-B Weight management composition 爱瑟金股份有限公司 2026-05-12 CN disclosed
CN-113366316-B Methods and compositions for identifying whether a subject with cancer will acquire a response to an immune checkpoint inhibitor 国家医疗保健研究所 2025-05-23 CN disclosed
CN-120018842-A Combination therapy for the treatment of cancer 国家医疗保健研究所 2025-05-16 CN disclosed
CN-113508129-B Mutant interleukin-34 (IL-34) polypeptides and their use in therapy 法国国家健康和医学研究院 2025-02-18 CN disclosed
CN-112955462-B Combination of a beta IG-H3 antagonist and an immune checkpoint inhibitor for the treatment of solid tumors 国家医疗保健研究所 2024-05-07 CN disclosed
CN-115997123-A Methods for predicting risk of recurrence and/or death of solid cancer patients after preoperative adjuvant therapy 国家医疗保健研究所 2023-04-21 CN disclosed
CN-115843335-A Method for predicting the risk of relapse and/or death of a patient with solid cancer after preoperative adjuvant and radical surgery 国家医疗保健研究所 2023-03-24 CN disclosed
CN-115198018-A Method for classifying patients with solid cancer 法国国家卫生及研究医学协会 2022-10-18 CN disclosed
CN-109690314-B Method for classifying patients with solid cancer 法国国家卫生及研究医学协会 2022-08-02 CN disclosed
CN-111867679-A SETDB1 histone methyltransferase inhibitors for combination cancer therapy 居里研究所 2020-10-30 CN disclosed
CN-111393351-A 2, 3-diiminoindole and 2, 3-diaminoindole derivatives 江西师范大学 2020-07-10 CN disclosed
CN-111032025-A Use of an inhibitor of SUV39H1 histone methyltransferase in the combination therapy of cancer 居里研究所 2020-04-17 CN disclosed
CN-109690314-A Method for classifying patients with solid cancer 法国国家卫生及研究医学协会 2019-04-26 CN disclosed
CN-108699154-A There is the antibody and application thereof of specificity to BTLA 国家医疗保健研究所 2018-10-23 CN disclosed
CN-1794986-B Novel medicine for the treatment of cancer LANKENAU INST MEDICAL RES 2012-09-05 CN disclosed
EP-1978930-A2 SUTURES AND ANTI-SCARRING AGENTS Angiotech Pharmaceuticals, Inc. (CA) 2008-10-15 EP disclosed
WO-2007089878-A2 SUTURES AND ANTI-SCARRING AGENTS ANGIOTECH PHARMACEUTICALS, INC. (CA) 2007-08-09 WO disclosed
CN-1794986-A Novel methods for the treatment of cancer LANKENAU INST MEDICAL RES (US) 2006-06-28 CN disclosed
CN-1003855-B Process for preparing 1, 3-disubstituted 2-oxindoles 美国辉瑞有限公司 1989-04-12 CN disclosed