SCHEMBL5066046

SCHEMBL5066046

O=C(CN1C(=O)CN(CCCNC2=NCCN2)C1=O)NCC(NC(=O)C(=O)c1ccccc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ITGAV P06756 20/20 0.52
▸ ITGB3 P05106 18/20 0.52
▸ ITGA2B P08514 4/20 0.38
▸ ITGB1 P05556 2/20 0.36
▸ ITGB5 P18084 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL606801 1.00 ITGAV (0.52) ITGAVITGB3ITGA2BITGB1ITGB5
SCHEMBL7212659 0.90 ITGAV (0.56) ITGAVITGB3ITGA2BITGB1
SCHEMBL7217721 0.87 ITGB3 (0.70) ITGAVITGB3ITGA2B
SCHEMBL7211708 0.81 ITGB3 (0.76) ITGAVITGB3ITGA2B
SCHEMBL7216496 0.75 ITGB3 (0.68) ITGAVITGB3ITGA2B
SCHEMBL7211353 0.73 ITGB3 (0.66) ITGAVITGB3ITGA2B
SCHEMBL7212726 0.70 ITGB3 (0.53) ITGAVITGB3ITGA2B
SCHEMBL7212708 0.69 ITGB3 (0.58) ITGAVITGB3ITGA2B
SCHEMBL7974391 0.69 ITGB3 (0.52) ITGAVITGB3ITGA2B
SCHEMBL244300 0.69 ITGB3 (1.00) ITGAVITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1978930-A2 SUTURES AND ANTI-SCARRING AGENTS Angiotech Pharmaceuticals, Inc. (CA) 2008-10-15 — — EP disclosed
WO-2007089878-A2 SUTURES AND ANTI-SCARRING AGENTS ANGIOTECH PHARMACEUTICALS, INC. (CA) 2007-08-09 — — WO disclosed
EP-1796602-A2 MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE Angiotech Pharmaceuticals (US), Inc. (US) 2007-06-20 — — EP disclosed
WO-2006083260-A2 COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE ANGIOTECH BIOMATERIALS CORPORATION (US) 2006-08-10 — — WO disclosed
WO-2006078282-A2 COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE ANGIOTECH BIOMATERIALS CORPORATION (US) 2006-07-27 — — WO disclosed
WO-2006034128-A2 MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE ANGIOTECH BIOMATERIALS CORPORATION (US) 2006-03-30 — — WO disclosed
WO-2005051232-A2 SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-06-09 — — WO disclosed
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