Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958348 | 0.96 | TSHR (0.63) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11552072 | 0.92 | TSHR (0.69) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL85965 | 0.92 | TSHR (0.75) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL19678288 | 0.91 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12607036 | 0.90 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL2033933 | 0.90 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL939180 | 0.90 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL26002001 | 0.86 | TSHR (0.78) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL26002003 | 0.86 | TSHR (0.78) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5973493 | 0.85 | ATM (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004050-B1 | CYANOSTILBENES | ROLIC TECH AG (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083655-A1 | CYANOSTILBENES | LATS1, LATS2, CRY1 | TSHR 4718/4885ALDH1A1 2838/4885TP53 2241/4885 |
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | TSHR 4718/4885ALDH1A1 2838/4885TP53 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.