Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060493 | 1.00 | HRH1 (0.63) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL9749942 | 1.00 | HRH1 (0.63) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5056472 | 0.94 | HRH1 (0.66) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5056474 | 0.94 | HRH1 (0.66) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL8782255 | 0.94 | HRH1 (0.66) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5056486 | 0.92 | AKR1B1 (0.61) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL9749982 | 0.92 | AKR1B1 (0.61) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5056479 | 0.92 | AKR1B1 (0.61) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5056626 | 0.89 | HRH1 (0.51) | HRH1LMNAPARP1 | |
| SCHEMBL9750021 | 0.89 | HRH1 (0.51) | HRH1LMNAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139531-A1 | USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR | ALCON MANUFACTURING LTD. (US) | 2008-06-12 | — | — | US | claimed |
| US-20080139531-A1 | USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR | ALCON MANUFACTURING LTD. (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139531-A1 | USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR | CMA1, LTK, KIT | HRH1 35/4885LMNA 3550/4885AKR1B1 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.