Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056472 | 1.00 | HRH1 (0.66) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5056474 | 1.00 | HRH1 (0.66) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5066508 | 0.94 | HRH1 (0.63) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5060493 | 0.94 | HRH1 (0.63) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL9749942 | 0.94 | HRH1 (0.63) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5060821 | 0.92 | AKR1B1 (0.64) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL9750101 | 0.92 | AKR1B1 (0.64) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5060820 | 0.92 | AKR1B1 (0.64) | HRH1LMNAAKR1B1PARP1 | |
| SCHEMBL5066504 | 0.90 | HRH1 (0.56) | HRH1LMNAAKR1B1 | |
| SCHEMBL9750094 | 0.90 | HRH1 (0.56) | HRH1LMNAAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235796-B2 | Dibenz [b,e] oxepin derivative and antiallergic and antiinflammatory agent | KYOWA HAKKO KOGYO KK (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5116863-A | Antiallergens, antiinflammatory agents; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |