Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205305 | 0.85 | HPGD (0.47) | HPGDHTTTP53ALDH1A1CNR2 | |
| SCHEMBL7203923 | 0.83 | CNR2 (0.47) | HPGDHTTTP53ALDH1A1CNR2 | |
| SCHEMBL4803721 | 0.81 | LSS (0.55) | ALDH1A1LSS | |
| SCHEMBL4803715 | 0.81 | LSS (0.55) | ALDH1A1LSS | |
| SCHEMBL7211522 | 0.80 | USP30 (0.44) | HPGDHTTALDH1A1CNR2L3MBTL1 | |
| SCHEMBL7204735 | 0.79 | CA1 (0.43) | HPGDHTTALDH1A1CNR2GBA1 | |
| SCHEMBL4798719 | 0.78 | LSS (0.55) | LSS | |
| SCHEMBL5070017 | 0.78 | LSS (0.45) | HPGDHTTALDH1A1CNR2GBA1 | |
| SCHEMBL4798709 | 0.78 | LSS (0.55) | LSS | |
| SCHEMBL4797875 | 0.77 | LSS (0.56) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-B1 | AMINOCYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-08-06 | — | — | EP | disclosed |