Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665699 | 1.00 | TYR (0.45) | TYRGPR84SCN5AHTR1AESR1 | |
| SCHEMBL5318185 | 1.00 | TYR (0.45) | TYRGPR84SCN5AHTR1AESR1 | |
| SCHEMBL6021257 | 1.00 | TYR (0.45) | TYRGPR84SCN5AHTR1AESR1 | |
| SCHEMBL9308493 | 0.89 | TYR (0.39) | TYRGPR84HTR1AESR1ESR2 | |
| SCHEMBL10774938 | 0.87 | TYR (0.41) | TYRGPR84SCN5AHTR1AESR1 | |
| SCHEMBL10603032 | 0.83 | GPR84 (0.43) | TYRGPR84HTR1AESR1ALDH1A1 | |
| SCHEMBL9803051 | 0.81 | GPR84 (0.41) | TYRGPR84HTR1ALMNASPHK1 | |
| SCHEMBL29174139 | 0.79 | TSHR (0.44) | TYRSCN5AESR1ESR2ALDH1A1 | |
| SCHEMBL5269801 | 0.78 | TYR (0.40) | TYRGPR84HTR1AESR1ESR2 | |
| SCHEMBL29282114 | 0.78 | TYR (0.41) | TYRSCN5AHTR1AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274925-A1 | Alkylated Pana and Dpa Compositions | CIBA SPECIALTY CHEMICALS CORP. | 2008-11-06 | — | — | US | disclosed |
| US-20070027252-A1 | Process for improving color of polycondensates | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-02-01 | — | — | US | disclosed |