⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881128 | 0.69 | — | — | |
| SCHEMBL3280535 | 0.66 | — | — | |
| SCHEMBL8429000 | 0.65 | — | — | |
| SCHEMBL5549694 | 0.64 | — | — | |
| SCHEMBL28537961 | 0.64 | — | — | |
| SCHEMBL28517011 | 0.63 | — | — | |
| SCHEMBL5549689 | 0.63 | — | — | |
| SCHEMBL10531371 | 0.62 | MAOA (0.32) | — | |
| SCHEMBL6452578 | 0.62 | CFTR (0.31) | — | |
| SCHEMBL6391069 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518756-B2 | Arylation method | UMICORE AG & CO. KG (DE) | 2022-12-06 | — | — | US | claimed |
| EP-3383861-B1 | BUCHWALD-HARTWIG ARYLATION METHOD FOR THE PREPARATION OF TERTIARY AMINES | UMICORE AG & CO KG (DE) | 2021-03-17 | — | — | EP | claimed |
| CN-111718281-A | Synthetic structural unit for preparing material for organic electroluminescent device | 默克专利有限公司 | 2020-09-29 | — | — | CN | claimed |
| US-20200031803-A1 | ARYLATION METHOD | UMICORE AG & CO. KG (DE) | 2020-01-30 | — | — | US | claimed |
| CN-105658627-B | Monoarylation of Aromatic Amines | 优美科股份公司及两合公司 | 2019-09-10 | — | — | CN | claimed |
| CN-106242938-B | Fluorene ethylene derivative and synthetic method thereof | 沈阳大学 | 2019-04-23 | — | — | CN | claimed |
| CN-108779105-A | Buchwald-Hartwig arylation methods are used to prepare tertiary aromatic amine | 优美科股份公司及两合公司 | 2018-11-09 | — | — | CN | claimed |
| EP-3060548-B1 | MONO ARYLATION OF AROMATIC AMINES | UMICORE AG & CO KG (DE) | 2018-10-10 | — | — | EP | claimed |
| CN-105684098-B | The good electrode of light transmittance, preparation method and the electronic component including it | 万斯有限公司 | 2018-10-02 | — | — | CN | claimed |
| CN-104211677-B | A kind of preparation method of anti-hepatitis C pharmaceutical intermediate | 浙江九洲药业股份有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-102209714-A | Triazine, pyrimidine and pyridine analogs and their use as therapeutic agents and diagnostic probes | UNIV BASEL | 2011-10-05 | — | — | CN | claimed |
| CN-101906134-A | Peptidic compounds | UNIV WOLLONGONG | 2010-12-08 | — | — | CN | claimed |
| CN-100452474-C | Luminous device and method for making same | SEMICONDUCTOR ENERGY LAB (JP) | 2009-01-14 | — | — | CN | claimed |
| WO-2008059342-A2 | METHOD OF TREATING A MATERIAL, THE SO OBTAINED TREATED MATERIAL AND DEVICES CONTAINING SAID MATERIAL | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) | 2008-05-22 | — | — | WO | claimed |
| CN-101142175-A | Peptide compounds | PEPTIDIC COMPOUNDS (AU) | 2008-03-12 | — | — | CN | claimed |
| WO-2006070381-A1 | AMINO-FUNCTIONALIZED 1,2,4-TRIOXANES USEFUL AS ANTI-MALARIAL AGENTS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-07-06 | — | — | WO | claimed |
| US-7071226-B1 | Amino-functionalized 1,2,4-trioxanes useful as antimalarial agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-07-04 | — | — | US | claimed |
| US-20060142378-A1 | AMINO-FUNCTIONALIZED 1,2,4-TRIOXANES USEFUL AS ANTIMALARIAL AGENTS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-06-29 | — | — | US | claimed |
| CN-1386587-A | Luminous device and method for making same | SEMICONDUCTOR ENERGY LAB (JP) | 2002-12-25 | — | — | CN | claimed |
| US-5958930-A | TREATING CANCER, AND SECONDARY INFECTIONS CAUSED BY PNEUMOCYSTIS CARINII AND TOXOPLASMOSIS GONDII IN IMMUNOCOMPROMISED PATIENTS. | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 1999-09-28 | — | — | US | claimed |