Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21327777 | 0.89 | TSHR (0.40) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL25211268 | 0.84 | TSHR (0.36) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL28034730 | 0.84 | TSHR (0.41) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL11416391 | 0.83 | ALDH1A1 (0.42) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL1970400 | 0.83 | TSHR (0.35) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL525459 | 0.83 | ALDH1A1 (0.42) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL3750987 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL18839942 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL636117 | 0.81 | ALDH1A1 (0.39) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL16424440 | 0.80 | TSHR (0.60) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080289539-A1 | COATING COMPOSITIONS HAVING HYPERBRANCHED POLYMERS AND METHODS OF PRODUCING SAME | BASF CORPORATION (US) | 2008-11-27 | — | — | US | claimed |
| US-20080289539-A1 | COATING COMPOSITIONS HAVING HYPERBRANCHED POLYMERS AND METHODS OF PRODUCING SAME | BASF CORPORATION (US) | 2008-11-27 | — | — | US | disclosed |