Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628238 | 1.00 | QPCTL (1.00) | QPCTLQPCT | |
| SCHEMBL14012458 | 1.00 | QPCTL (1.00) | QPCTLQPCT | |
| SCHEMBL14012457 | 0.90 | QPCTL (1.00) | QPCTLQPCT | |
| SCHEMBL3633424 | 0.90 | QPCTL (1.00) | QPCTLQPCT | |
| SCHEMBL5064458 | 0.90 | QPCTL (1.00) | QPCTLQPCT | |
| SCHEMBL10144452 | 0.84 | QPCTL (0.73) | QPCTLQPCT | |
| SCHEMBL3661669 | 0.84 | QPCTL (0.73) | QPCTLQPCT | |
| SCHEMBL3661673 | 0.84 | QPCTL (0.73) | QPCTLQPCT | |
| SCHEMBL14012459 | 0.83 | QPCTL (1.00) | QPCTLQPCT | |
| SCHEMBL5063790 | 0.83 | QPCTL (1.00) | QPCTLQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772508-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2014-07-08 | — | — | US | claimed |
| EP-2142513-B1 | NITROVINYL-DIAMINE DERIVATIVES AS GLUTAMINYL CYCLASE INHIBITORS | PROBIODRUG AG (DE) | 2014-03-12 | — | — | EP | claimed |
| US-8772508-B2 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2014-07-08 | — | — | US | disclosed |
| EP-2142513-B1 | NITROVINYL-DIAMINE DERIVATIVES AS GLUTAMINYL CYCLASE INHIBITORS | PROBIODRUG AG (DE) | 2014-03-12 | — | — | EP | disclosed |
| US-20080292582-A1 | imidazole derivatives; Alzheimer's Disease, Down syndrome and Huntington's Disease; hypotensive agents; sleeping and eating disorders, anxiolytic agents, antidepressants, antiepileptic agents; drug abuse/withdrawl; 1-(3,4-dimethoxyphenyl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)thiourea | PROBIODRUG AG (DE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292582-A1 | imidazole derivatives; Alzheimer's Disease, Down syndrome and Huntington's Disease; hypotensive agents; sleeping and eating disorders, anxiolytic agents, antidepressants, antiepileptic agents; drug abuse/withdrawl; 1-(3,4-dimethoxyphenyl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)thiourea | HTT, MAPT, HYPK | QPCTL 3689/4885QPCT 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.