Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29157932 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6407177 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL31571631 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL4415753 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9465334 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9178578 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL31571632 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9145494 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL532723 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1331961 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756156-A | Nanometer barium calcium carbonate solid solution, preparation method and application thereof | 福建贝思科电子材料股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-108544131-A | A kind of stainless steel electrode for manufacturing office equipment | 安徽华普生产力促进中心有限公司 | 2018-09-18 | — | — | CN | claimed |
| CN-108182983-A | A kind of administering method of uranium purifying radioactive wastewater | 北京航天新风机械设备有限责任公司 | 2018-06-19 | — | — | CN | claimed |
| CN-103342451-A | Manufacturing method for lead-free sealing glass with transitional expansion coefficient | SHANDONG KANGYOU GLASS MATERIAL CO LTD | 2013-10-09 | — | — | CN | claimed |
| CN-101759202-B | Method for removing sulfate radicals in saline water by using liquid barium chloride | Xinjiang shihezi zhongfa chemical co ltd | 2012-01-25 | — | — | CN | claimed |
| CN-101759202-A | Method for removing sulfate radicals in saline water by using liquid barium chloride | XINJIANG SHIHEZI ZHONGFA CHEMI | 2010-06-30 | — | — | CN | claimed |
| US-20080069728-A1 | SYSTEM AND METHOD FOR ANALYZING SAMPLES THAT CAN BE MADE TO EMIT GAS | MIPS TECHNOLOGIES, INC. | 2008-03-20 | — | — | US | claimed |
| US-5200452-A | Nontoxic, self-extinguishing, high workability blends | GURIT-ESSEX AG (CH) | 1993-04-06 | — | — | US | claimed |
| JP-8188983-A | — | — | None | — | — | JP | disclosed |
| CN-117756156-B | Nanometer barium calcium carbonate solid solution, preparation method and application thereof | 福建贝思科电子材料股份有限公司 | 2025-10-28 | — | — | CN | disclosed |
| CN-117756156-B | Nanometer barium calcium carbonate solid solution, preparation method and application thereof | 福建贝思科电子材料股份有限公司 | 2025-10-28 | — | — | CN | disclosed |
| CN-119661145-A | Concrete for resisting carbon sulfur tobermorite sulfate erosion and preparation method thereof | 江苏京沪高速公路有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-117756156-A | Nanometer barium calcium carbonate solid solution, preparation method and application thereof | 福建贝思科电子材料股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117756156-A | Nanometer barium calcium carbonate solid solution, preparation method and application thereof | 福建贝思科电子材料股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-4954625-A | ENZYME INHIBITORS, HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| CN-1043483-A | The method for making of barium carbonate | TIANJIN CHEMICAL INDUSTRY INST (CN) | 1990-07-04 | — | — | CN | disclosed |
| EP-0342788-A1 | Synthetic resin composition | Bridgestone Corporation (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4871842-A | Piperidine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4816466-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0187037-A2 | Piperidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-07-09 | — | — | EP | disclosed |