Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8435181 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3266233 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7926706 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL711064 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9145494 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9146197 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8059663 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3261 | 1.00 | — | — | |
| Bicarbonate SCHEMBL1331961 | 1.00 | — | — | |
| Bicarbonate SCHEMBL1537736 | 1.00 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4477987-B1 | WAD FOR SHOT OR BULLET CARTRIDGE, SHOT OR BULLET CARTRIDGE COMPRISING SUCH A WAD, AND METHODS FOR PRODUCING SAID WAD AND BULLET CARTRIDGE | DECATHLON SA (FR) | 2025-10-08 | — | — | EP | claimed |
| EP-2632504-B2 | COMPOSITES OF HYDROXYAPATITE AND CALCIUM CARBONATE AND RELATED METHODS OF PREPARATION AND USE | CAP BIOMATERIALS LLC (US) | 2025-04-02 | — | — | EP | claimed |
| EP-4299063-B1 | ORAL CAPSULES COMPRISING ATORVASTATIN TABLETS SHOWING SUITABLE DISSOLUTION PROFILE AND BIOAVAILABILITY | FERRER INT (ES) | 2024-05-01 | — | — | EP | claimed |
| CN-114767719-B | A pharmaceutical composition for preventing and treating rickets, and its preparation method | 北京朗迪制药有限公司 | 2023-01-17 | — | — | CN | claimed |
| EP-3850270-B1 | A METHOD OF OPERATING AN INCINERATOR COMPRISING A DEVICE FOR CAPTURING ASH ENTRAINED BY FLUE GAS | MINPLUS B V (NL) | 2022-11-02 | — | — | EP | claimed |
| US-11382928-B2 | Nutritional composition with resistant starch useful in the treatment of neoplastic diseases | Fondazione di Religione e di Culto Casa Sollievo Della Soffernza—Opera di San Pio da Pietrelcina (IT) | 2022-07-12 | — | — | US | claimed |
| EP-3544630-B1 | NUTRITIONAL COMPOSITION WITH RESISTANT STARCH USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | FOND DI RELIGIONE E DI CULTO CASA SOLLIEVO DELLA SOFFERENZA OPERA DI SAN PIO DA PIETRELCINA (IT) | 2021-03-24 | — | — | EP | claimed |
| WO-2021039892-A1 | MEDICAL CALCIUM CARBONATE COMPOSITION, RELATED MEDICAL COMPOSITIONS, AND PRODUCTION METHODS THEREFOR | 石川 邦夫 | 2021-03-04 | — | — | WO | claimed |
| CN-110508363-A | The product of the clean mill of rue and its application method and the clean mill processing of rue | KUNMING TEKANG SCIENCE & TECH CO LTD | 2019-11-29 | — | — | CN | claimed |
| US-20190343866-A1 | NUTRITIONAL COMPOSITION WITH RESISTANT STARCH USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | FONDAZIONE DI RELIGIONE E DI CULTO "CASA SOLLIEVO DELLA SOFFERENZA" - OPERA DI SAN PIO DA PIETRELCINA (IT) | 2019-11-14 | — | — | US | claimed |
| CN-106957394-A | A kind of polycarboxylic-acid hyper-dispersant and its preparation method and application | 芜湖弘马新材料有限公司 | 2017-07-18 | — | — | CN | claimed |
| CN-104080740-B | Method for producing an aqueous solution containing at least one earth alkali hydrogen carbonate and use thereof | OMYA国际股份公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103074803-B | Print with unglazed coating paper | 王子控股株式会社 | 2016-09-14 | — | — | CN | claimed |
| CN-105778325-A | Environment-friendly automotive wire PVC casing material and preparation method thereof | 上海凯波特种电缆料厂有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-105461246-A | Cement additive and preparation method thereof | WANG XIAOWEI | 2016-04-06 | — | — | CN | claimed |
| CN-103445189-A | Special marine albumen powder for middle-aged and old people and preparation method thereof | QINGDAO BETTER BIO TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | claimed |
| US-8597703-B2 | Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2013-12-03 | — | — | US | claimed |
| CN-102327809-B | Method for removing magnesium oxide from collophanite | HUNAN INST FOR ANALYZING AND UTILIZING MINERAL RESOURCE | 2013-05-01 | — | — | CN | claimed |
| US-20100212853-A1 | Fiber loading improvements in papermaking | GEORGIA TECH RESEARCH CORPORATION | 2010-08-26 | — | — | US | claimed |
| US-5833958-A | NO ANIONS PRESENT TO INHIBIT THE EFFECTIVENESS OF LANTHOCIN TYPE BACTERIOCIN ANTIBACTERIAL AGENTS NISIN, GRAMICIDIN, AND TYROTHRICIN | AMBI INC. (US) | 1998-11-10 | — | — | US | claimed |