Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | AKT2 | P31751 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810694 | 0.93 | PIM1 (0.61) | PIM1AKT2EGFR | |
| SCHEMBL5064931 | 0.92 | PIM1 (0.59) | PIM1AKT2EGFR | |
| SCHEMBL5065555 | 0.90 | PIM1 (0.70) | PIM1AKT2EGFRFBP1 | |
| SCHEMBL5061756 | 0.88 | PIM1 (0.54) | PIM1AKT2EGFR | |
| SCHEMBL810232 | 0.87 | PIM1 (0.57) | PIM1AKT2EGFR | |
| SCHEMBL810039 | 0.86 | PIM1 (0.62) | PIM1AKT2EGFR | |
| SCHEMBL4976018 | 0.86 | PIM1 (0.54) | PIM1AKT2EGFRFBP1 | |
| SCHEMBL810944 | 0.86 | PIM1 (0.64) | PIM1AKT2EGFR | |
| SCHEMBL811615 | 0.85 | PIM1 (0.55) | PIM1AKT2EGFR | |
| SCHEMBL821092 | 0.84 | PIM1 (0.57) | PIM1AKT2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |