Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 8/20 | 0.52 |
| ▸ | GLA | P06280 | 8/20 | 0.52 |
| ▸ | STS | P08842 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140039 | 0.88 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL29391759 | 0.88 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| Phosphoric Acid SCHEMBL9224251 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL4610846 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL1873746 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL29374108 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL6994348 | 0.78 | KDM4E (0.78) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| Choline SCHEMBL10006627 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7643428 | 0.78 | AR (0.54) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL9751573 | 0.77 | ALDH1A1 (0.82) | ALDH1A1KDM4EHSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118324-A2 | COMPOSITION AND METHOD OF TREATING CANCER WITH AN ANTI-UROPLAKIN IB ANTIBODY | MACROGENICS, INC. (US) | 2008-10-02 | — | — | WO | disclosed |