Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL311029 | 0.96 | — | — | |
| Acrylic Acid SCHEMBL311952 | 0.96 | — | — | |
| Acrylic Acid SCHEMBL30708619 | 0.96 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL28880884 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL29271057 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL28977362 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL10714144 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL29516833 | 0.92 | LMNA (0.50) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL184246 | 0.88 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL16257 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |