Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 14/20 | 0.40 |
| ▸ | KLRK1 | P26718 | 4/20 | 0.36 |
| ▸ | MICA | Q29983 | 4/20 | 0.36 |
| ▸ | RAET1L | Q5VY80 | 4/20 | 0.36 |
| ▸ | APOB | P04114 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069283 | 0.76 | MTTP (0.48) | MTTPKLRK1MICARAET1L | |
| SCHEMBL5068026 | 0.75 | MTTP (0.42) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL3737870 | 0.75 | MTTP (0.48) | MTTPKLRK1MICARAET1L | |
| SCHEMBL5065061 | 0.75 | MTTP (0.43) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL403325 | 0.74 | MTTP (0.47) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL14031482 | 0.74 | MTTP (0.42) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL5061989 | 0.73 | MTTP (0.45) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL14031572 | 0.72 | MTTP (0.53) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL5064986 | 0.72 | MTTP (0.48) | MTTPKLRK1MICARAET1LAPOB | |
| SCHEMBL402457 | 0.72 | MTTP (0.48) | MTTPKLRK1MICARAET1LAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432392-B2 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2008-10-07 | — | — | US | disclosed |
| US-20060205726-A1 | Ester derivatives and medical use thereof | JAPAN TOBACCO INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1669345-A1 | ESTER DERIVATIVE AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2006-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205726-A1 | Ester derivatives and medical use thereof | MTTP, LIPC, CETP | MTTP 1/4885KLRK1 3940/4885MICA 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.