Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5066763 | 0.83 | POLB (0.45) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL8570609 | 0.81 | MAPT (0.62) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL13501425 | 0.78 | HSD17B10 (0.60) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL21775472 | 0.77 | MAPT (0.57) | MAPTKDM4ESMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL12091143 | 0.77 | MAPT (0.48) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5055343 | 0.77 | MAPT (0.60) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL1665475 | 0.76 | MAPT (0.63) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL3559993 | 0.76 | HSD17B10 (0.58) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL5071859 | 0.76 | MAPT (0.58) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL8928795 | 0.76 | MAPT (0.52) | MAPTHSD17B10KDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |