Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713324 | 0.90 | MAPT (0.60) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL9332678 | 0.89 | POLB (0.61) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL8897411 | 0.86 | HTT (0.57) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL8897407 | 0.86 | HTT (0.57) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL9499865 | 0.86 | TDP1 (0.57) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL10333121 | 0.86 | HTT (0.57) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL9499693 | 0.86 | TDP1 (0.57) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL10485764 | 0.85 | TDP1 (0.56) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL9133114 | 0.85 | PTGS2 (0.56) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL22490709 | 0.82 | TSHR (0.69) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |