Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.82 |
| ▸ | RAB9A | P51151 | 8/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.82 |
| ▸ | HPGD | P15428 | 5/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.64 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344809 | 0.88 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL29432093 | 0.86 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL18825839 | 0.86 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL2303449 | 0.84 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL758308 | 0.80 | CYP1A2 (0.77) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL18826019 | 0.78 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL18787654 | 0.78 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL5070873 | 0.75 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL5071859 | 0.74 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL3705489 | 0.74 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2908843-B1 | TREATING CANCER | AGENCY SCIENCE TECH & RES (SG) | 2019-09-04 | — | — | EP | claimed |
| EP-1595866-B1 | Cyanopyrrolidines useful for the treatment of inter alia metabolic syndrome | SANWA KAGAKU KENKYUSHO CO (JP) | 2016-06-08 | — | — | EP | disclosed |
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | DPP4, DPP3, DPP7 | NPC1 371/4885RAB9A 3667/4885SMN1; SMN2 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.