Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375778 | 0.77 | MAPK14 (0.42) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| SCHEMBL1504495 | 0.74 | TTR (0.46) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL375156 | 0.74 | MAPK14 (0.40) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| SCHEMBL2031253 | 0.73 | MAPK14 (0.46) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| SCHEMBL2031249 | 0.73 | MAPK14 (0.46) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| Hydrochloric Acid SCHEMBL2029284 | 0.73 | MAPK13 (0.41) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| SCHEMBL1504761 | 0.73 | ALDH1A1 (0.38) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL2031835 | 0.70 | MAPK13 (0.43) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| SCHEMBL2031836 | 0.70 | MAPK13 (0.43) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| SCHEMBL1504529 | 0.70 | ALDH1A1 (0.46) | MAPK14ALDH1A1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932840-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-18 | — | — | EP | disclosed |