Styrene

Styrene

SCHEMBL5069332

C=CC(=O)C(=C)C#N.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TSHR P16473 1/20 0.45
MCL1 Q07820 2/20 0.39
AKT1 P31749 1/20 0.35
LMNA P02545 4/20 0.33
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
PLIN1 O60240 2/20 0.33
PLIN5 Q00G26 2/20 0.33
ABHD5 Q8WTS1 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 4/20 0.33
HTT P42858 1/20 0.33
HPGD P15428 1/20 0.33
TGM2 P21980 1/20 0.33
KMT2A Q03164 4/20 0.32
PKM P14618 2/20 0.32
POLB P06746 1/20 0.32
HDAC3 O15379 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4171118 0.97 ALDH1A1 (0.48) ALDH1A1TSHRMCL1AKT1LMNA
Styrene SCHEMBL1690912 0.84 ALDH1A1 (0.45) ALDH1A1TSHRMCL1LMNAMAPT
Styrene SCHEMBL16194120 0.81 ALDH1A1 (0.58) ALDH1A1TSHRMCL1LMNAMAPT
Styrene SCHEMBL5675050 0.80 ALDH1A1 (0.52) ALDH1A1TSHRMCL1AKT1LMNA
Styrene SCHEMBL27752708 0.78 ALDH1A1 (0.67) ALDH1A1TSHRMCL1AKT1LMNA
Styrene SCHEMBL341005 0.78 ALDH1A1 (0.50) ALDH1A1TSHRMCL1AKT1LMNA
Styrene SCHEMBL28774655 0.78 ALDH1A1 (0.54) ALDH1A1TSHRMCL1LMNAMAPT
Styrene SCHEMBL353087 0.78 ALDH1A1 (0.54) ALDH1A1TSHRMCL1MAPTSMN1; SMN2
Styrene SCHEMBL157052 0.78 ALDH1A1 (0.54) ALDH1A1TSHRMCL1AKT1LMNA
Styrene SCHEMBL25347029 0.77 ALDH1A1 (0.45) ALDH1A1TSHRMCL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933183-B1 SHEET FOR MOLDED-IN FOIL DECORATION AND METHOD OF PRODUCING MOLDED RESIN HAVING MOLDED-IN FOIL DECORATION BY USING THE SHEET NISSHA PRINTING (JP) 2008-11-19 EP disclosed
US-6866938-B2 Foil-detecting sheet and method of producing a foil-decorated resin article using the same NISSHA PRINTING CO., LTD. (JP) 2005-03-15 US disclosed
US-20020058144-A1 Foil-decorating sheet and method of producing a foil-decorated resin article using the same NISSHA PRINTING CO., LTD. (JP) 2002-05-16 US disclosed
US-6326086-B1 TRANSPARENT ACRYLIC FILM LAMINATED ON POLYPROPYLENE RESIN LOADED WITH A STYRENE ELASTOMER USED FOR THREE-DIMENSIONAL SHAPE AUTOMOTIVE TRIMS NISSHA PRINTING CO., LTD. (JP) 2001-12-04 US disclosed
EP-0933183-A1 SHEET FOR MOLDED-IN FOIL DECORATION AND METHOD OF PRODUCING MOLDED RESIN HAVING MOLDED-IN FOIL DECORATION BY USING THE SHEET NISSHA PRINTING CO., LTD. (JP) 1999-08-04 EP disclosed