Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939853 | 0.87 | SRD5A1 (0.55) | KMT2ASRD5A1SRD5A2 | |
| SCHEMBL9275243 | 0.86 | SRD5A1 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL4265528 | 0.83 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL13656758 | 0.83 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL7751282 | 0.83 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL4265525 | 0.83 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL9022350 | 0.76 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL9022344 | 0.76 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL3652868 | 0.72 | CYP19A1 (0.60) | CYP19A1ARNR3C1SHBGPGR | |
| SCHEMBL3652870 | 0.72 | CYP19A1 (0.60) | CYP19A1ARNR3C1SHBGPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467739-A4 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1467739-A2 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2004-10-20 | — | — | EP | claimed |
| WO-2003059293-A2 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-07-24 | — | — | WO | claimed |