Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B7 | P56937 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275243 | 0.94 | SRD5A1 (0.57) | SRD5A1HSD17B7SRD5A2 | |
| SCHEMBL5069374 | 0.87 | CYP19A1 (0.53) | SRD5A1KMT2ASRD5A2 | |
| SCHEMBL4265528 | 0.84 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL4265525 | 0.84 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL7751282 | 0.84 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL13656758 | 0.84 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL9022350 | 0.77 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL9022344 | 0.77 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL9065981 | 0.73 | SHBG (0.51) | SRD5A1KMT2AHSD17B7SRD5A2 | |
| SCHEMBL9065982 | 0.73 | SHBG (0.51) | SRD5A1KMT2AHSD17B7SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700291-A4 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0700291-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO. INC. (US) | 1996-03-13 | — | — | EP | disclosed |