Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071363 | 0.89 | CYP3A4 (0.79) | RENCYP3A4 | |
| SCHEMBL664460 | 0.88 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL664223 | 0.88 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL5069697 | 0.87 | CYP3A4 (0.77) | RENCYP3A4 | |
| SCHEMBL663349 | 0.86 | REN (0.71) | RENCYP3A4 | |
| SCHEMBL663466 | 0.86 | REN (0.73) | RENCYP3A4 | |
| SCHEMBL661927 | 0.86 | REN (0.68) | RENCYP3A4 | |
| SCHEMBL662754 | 0.83 | REN (0.85) | RENCYP3A4 | |
| SCHEMBL660892 | 0.83 | REN (0.69) | RENCYP3A4 | |
| SCHEMBL662969 | 0.83 | REN (0.73) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910272-A1 | RENIN INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2008-04-16 | — | — | EP | claimed |
| WO-2007009250-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2007-01-25 | — | — | WO | claimed |