Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 6/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.57 |
| ▸ | UQCRB | P14927 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14660188 | 0.89 | CCR9 (0.66) | CCR9HSD17B2UQCRBCA1CA2 | |
| SCHEMBL2530482 | 0.83 | CCR9 (0.81) | CCR9HSD17B2UQCRBCCR2PSD | |
| SCHEMBL15777052 | 0.83 | CCR9 (0.56) | CCR9HSD17B2UQCRBGLO1 | |
| SCHEMBL5628909 | 0.81 | CCR9 (0.49) | CCR9KDM4ETSHRPTK2BCCR2 | |
| SCHEMBL27490 | 0.79 | CCR9 (0.78) | CCR9HSD17B2CCR2LMNAHTT | |
| SCHEMBL12221304 | 0.79 | CCR9 (0.66) | CCR9HSD17B2UQCRBCCR2LMNA | |
| SCHEMBL7587850 | 0.77 | HSD17B2 (0.79) | HSD17B2UQCRBCA1CA2KDM4E | |
| SCHEMBL8278412 | 0.77 | TSHR (0.57) | KDM4ETSHRPTK2BCCR2ALDH1A1 | |
| SCHEMBL10222599 | 0.77 | CCR9 (0.55) | CCR9HSD17B2UQCRBCCR2LMNA | |
| SCHEMBL1104723 | 0.76 | CCR9 (0.56) | CCR9HSD17B2UQCRBPSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567486-B1 | BIS-ARYL SULFONAMIDES | CHEMOCENTRYX INC (US) | 2008-01-16 | — | — | EP | claimed |