Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035286 | 0.85 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7508195 | 0.80 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5406669 | 0.76 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28039850 | 0.75 | — | — | |
| SCHEMBL230818 | 0.74 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL13750180 | 0.72 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10915048 | 0.71 | — | — | |
| SCHEMBL7262723 | 0.70 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14566179 | 0.70 | — | — | |
| SCHEMBL28473633 | 0.69 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368519-B2 | Fast moisture curing and UV-moisture dual curing compositions | HENKEL CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| EP-1578810-B1 | FAST MOISTURE CURING AND UV-MOISTURE DUAL CURING COMPOSITIONS | HENKEL CORP (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1578810-A4 | FAST MOISTURE CURING AND UV-MOISTURE DUAL CURING COMPOSITIONS | HENKEL CORP (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20050267276-A1 | Fast moisture curing and uv-moisture dual curing compositions | HENKEL AG & CO. KGAA (DE) | 2005-12-01 | — | — | US | disclosed |
| EP-1578810-A1 | FAST MOISTURE CURING AND UV-MOISTURE DUAL CURING COMPOSITIONS | Henkel Corporation (US) | 2005-09-28 | — | — | EP | disclosed |
| US-6828355-B1 | Resin-reinforced silicone compositions curable upon exposure to radiation in the electromagnetic spectrum, which when cured demonstrate improved elastomeric properties, such as tensile strength, modulus and elongation | HENKEL CORPORATION | 2004-12-07 | — | — | US | disclosed |
| WO-2004037868-A1 | FAST MOISTURE CURING AND UV-MOISTURE DUAL CURING COMPOSITIONS | HENKEL CORPORATION (US) | 2004-05-06 | — | — | WO | disclosed |
| WO-2001005846-A1 | RESIN-REINFORCED UV, MOISTURE AND UV/MOISTURE DUAL CURABLE SILICONE COMPOSITIONS | LOCTITE CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |
| EP-0487291-B1 | Photocurable silicon composition, and method of making same | LOCTITE CORP (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5348986-A | Polysiloxanes capped with mixture of curable groups, gels, acrylated polymers | LOCTITE CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| US-5212211-A | Adhesives, coatings | LOCTITE CORPORATION (US) | 1993-05-18 | — | — | US | disclosed |
| US-5182315-A | Endcapping | LOCTITE CORPORATION (US) | 1993-01-26 | — | — | US | disclosed |
| US-5179134-A | Acryloyloxysilyl compound with a silicone and a photoinitiator for sealants, coatings and potting material which are curable | LOCTITE CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| EP-0487291-A2 | Photocurable silicon composition, and method of making same | LOCTITE CORPORATION (US) | 1992-05-27 | — | — | EP | disclosed |