SCHEMBL230818

SCHEMBL230818

C=CC(=O)OC[SiH2]OC(C)C

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
HPGD P15428 1/20 0.41
ALDH1A1 P00352 4/20 0.41
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
CYP3A4 P08684 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
THRB P10828 2/20 0.35
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5406669 0.79 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1014595 0.79 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28039850 0.78
SCHEMBL28035286 0.75 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL13750180 0.74 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3915278 0.74 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5069827 0.74 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL10915048 0.74
SCHEMBL5396543 0.73 TSHR (0.52) TSHRALDH1A1THRBTDP1
SCHEMBL7262723 0.73 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024221838-A1 POLYMER AND PREPARATION METHOD THEREFOR, GEL POLYMER ELECTROLYTE, BATTERY, AND ELECTRICAL DEVICE 宁德时代新能源科技股份有限公司 2024-10-31 WO claimed
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
CN-115558335-A Two-component recyclable surface printing delustering oil for BOPP treatment-free surface printing 浙江浦江永进工贸有限公司 2023-01-03 CN claimed
CN-115401060-A Method for removing chlorine content in organic hazardous waste 浙江红狮环保股份有限公司 2022-11-29 CN claimed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP claimed
CN-113372485-B Water-in-oil type nano emulsion, nano emulsion composite response type variable viscosity acid thickener and preparation method thereof 山东诺尔生物科技有限公司 2021-10-29 CN claimed
CN-113372485-A Water-in-oil type nano emulsion, nano emulsion composite response type variable viscosity acid thickener and preparation method thereof 山东诺尔生物科技有限公司 2021-09-10 CN claimed
CN-112029088-A Silane modified polyether based on Michael addition reaction and synthesis method thereof 郑州大学 2020-12-04 CN claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
CN-119773397-A Single-sided water-based environment-friendly hot-drawn film and preparation process thereof 东莞市赛越新材料科技有限公司 2025-04-08 CN disclosed
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-10-31 US disclosed
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-08-27 US disclosed
CN-117529524-A Curable composition and cured product 综研化学株式会社 2024-02-06 CN disclosed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP disclosed
EP-3624753-B1 DENTAL ADHESIVE COMPOSITION, PREPARATION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2022-03-30 EP disclosed
CN-113372485-B Water-in-oil type nano emulsion, nano emulsion composite response type variable viscosity acid thickener and preparation method thereof 山东诺尔生物科技有限公司 2021-10-29 CN disclosed
CN-113372485-A Water-in-oil type nano emulsion, nano emulsion composite response type variable viscosity acid thickener and preparation method thereof 山东诺尔生物科技有限公司 2021-09-10 CN disclosed
CN-111989348-A Polymer having reactive silicon-containing group and method for producing same 信越化学工业株式会社 2020-11-24 CN disclosed
US-20120004437-A1 METHOD FOR PRODUCING (METH)ACRYLOSILANES WACKER CHEMIE AG (DE) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials CDH1, F12, ACTN1 TSHR 4762/4885HPGD 336/4885ALDH1A1 78/4885
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A TSHR 705/4885HPGD 4304/4885ALDH1A1 1413/4885
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials CDH1, F12, ACTN1 TSHR 4762/4885HPGD 336/4885ALDH1A1 78/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.