SCHEMBL5070032

SCHEMBL5070032

CN1c2ccc(Oc3ccccc3)cc2N(C)c2ccc(Oc3ccccc3)cc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 2/20 0.51
LTA4H P09960 5/20 0.48
TSHR P16473 1/20 0.48
MAOB P27338 2/20 0.44
MAOA P21397 2/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
GSTP1 P09211 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MITF O75030 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
GFER P55789 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NLRP1 Q9C000 1/20 0.41
NOD2 Q9HC29 1/20 0.41
NTRK1 P04629 1/20 0.40
IGF1R P08069 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069919 0.98 GRIA2 (0.50) GRIA2LTA4HTSHRMAOBMAOA
SCHEMBL19532242 0.86 LTA4H (0.53) GRIA2LTA4HNR1H2MEN1KMT2A
SCHEMBL31134270 0.84 GRIA2 (0.41) GRIA2LTA4HTSHRMAOBMEN1
SCHEMBL22245096 0.83 SMN1; SMN2 (0.56) GRIA2LTA4HALDH1A1MAPTSMN1; SMN2
SCHEMBL25026563 0.82 SNCA (0.54) GRIA2LTA4HTSHRMAOBMAOA
SCHEMBL19532288 0.81 LTA4H (0.56) LTA4HNR1H2MEN1KMT2AMITF
SCHEMBL19532247 0.80 FFAR4 (0.43) GRIA2LTA4HTSHRGSTP1ALDH1A1
SCHEMBL19532267 0.80 LTA4H (0.42) GRIA2LTA4HGSTP1ALDH1A1SMN1; SMN2
SCHEMBL31067294 0.74 SNCA (0.47) GRIA2LTA4HTSHRMAOAGSTP1
SCHEMBL19532175 0.74 BRD4 (0.41) GRIA2NR1H2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7450293-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-11-11 US claimed
US-7436570-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-14 US claimed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP claimed
US-20050151467-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-07-14 US claimed
US-20050116627-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-06-02 US claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP claimed
WO-2004000800-A2 ELECTROCHROMIC SALTS, SOLUTIONS, AND DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-12-31 WO claimed
US-20030234379-A1 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC 2003-12-25 US claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US claimed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP claimed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US claimed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO claimed
EP-3320392-B1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGING APPARATUS, AND WINDOW MEMBER CANON KK (JP) 2021-10-27 EP disclosed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US disclosed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050151467-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 GRIA2 1640/4885LTA4H 4496/4885TSHR 3335/4885
US-20050116627-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 GRIA2 1640/4885LTA4H 4496/4885TSHR 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.