Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 14/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.67 |
| ▸ | HSD17B7 | P56937 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070238 | 1.00 | SRD5A1 (0.67) | SRD5A1SRD5A2HSD17B7 | |
| SCHEMBL7909915 | 0.85 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL9486929 | 0.85 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL7909909 | 0.85 | SRD5A1 (0.64) | SRD5A1SRD5A2 | |
| SCHEMBL8336441 | 0.81 | SRD5A1 (1.00) | SRD5A1SRD5A2 | |
| SCHEMBL917441 | 0.81 | SRD5A1 (1.00) | SRD5A1SRD5A2 | |
| SCHEMBL917440 | 0.81 | SRD5A1 (1.00) | SRD5A1SRD5A2 | |
| SCHEMBL5070908 | 0.80 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL5070909 | 0.80 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL4265525 | 0.78 | SRD5A1 (0.64) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467739-A4 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1467739-A2 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2004-10-20 | — | — | EP | claimed |
| WO-2003059293-A2 | 17-HYDROXY-4-AZA-ANDROSTAN-3-ONES AS ANDROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-07-24 | — | — | WO | claimed |