Metalaxyl

Metalaxyl

SCHEMBL5070290

COCC(=O)N(c1c(C)cccc1C)C(C)C(=O)OC.COCC(=O)N(c1c(C)cccc1C)[C@H](C)C(=O)OC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.58
MEN1 O00255 5/20 0.58
NPSR1 Q6W5P4 2/20 0.58
PLA2G1B P04054 1/20 0.58
HTT P42858 1/20 0.58
ATG4B Q9Y4P1 1/20 0.58
RORC P51449 1/20 0.44
NLRP3 Q96P20 5/20 0.39
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 1/20 0.37
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mefenoxam SCHEMBL22529 1.00 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL8376541 1.00 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL55820 1.00 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL20990 1.00 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL8817105 1.00 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL30058456 1.00 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL5075392 0.99 KMT2A (0.56) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL156622 0.99 KMT2A (0.56) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL8852635 0.97 KMT2A (0.55) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL9638629 0.97 KMT2A (0.55) KMT2AMEN1NPSR1PLA2G1BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116784339-A Pesticide composition and application thereof 山东省联合农药工业有限公司 2023-09-22 CN claimed
CN-115299444-B Composition containing trifloxystrobin and application thereof 山东省联合农药工业有限公司 2024-01-30 CN disclosed
CN-116784339-A Pesticide composition and application thereof 山东省联合农药工业有限公司 2023-09-22 CN disclosed
CN-116634876-A Mixtures and compositions comprising Fusarium A, fusarium B and fungicides 巴斯夫欧洲公司 2023-08-22 CN disclosed
EP-2579723-A2 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE DERIVATIVES Syngenta Participations AG (CH) 2013-04-17 EP disclosed
EP-2003973-A2 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDAL PROPERTIES Bayer CropScience AG (DE) 2008-12-24 EP disclosed
WO-2007112893-A2 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2007-10-11 WO disclosed
EP-1727804-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2006-12-06 EP disclosed
EP-1715743-A1 COMBINATIONS OF INSECTICIDE ACTIVE AGENTS BASED ON THIACLOPRID AND PYRETHROIDS Bayer CropScience Aktiengesellschaft (DE) 2006-11-02 EP disclosed
EP-1656382-A2 4-BIPHENYLSUBSTITUTED PYRAZOLIDIN-3,5-DIONE DERIVATIVES Bayer CropScience Aktiengesellschaft (DE) 2006-05-17 EP disclosed
WO-2005095351-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2005-10-13 WO disclosed
WO-2005077186-A1 COMBINATIONS OF INSECTICIDE ACTIVE AGENTS BASED ON THIACLOPRID AND PYRETHROIDS BAYER CROPSCIENCE AG (DE) 2005-08-25 WO disclosed
WO-2005016873-A2 4-BIPHENYLSUBSTITUTED PYRAZOLIDIN-3,5-DIONE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-02-24 WO disclosed
EP-1427288-A1 FUNGICIDE COMPOSITION COMPRISING PYRIMETHANIL AND IPRODIONE Bayer CropScience S.A. (FR) 2004-06-16 EP disclosed
WO-2003024228-A1 FUNGICIDAL COMPOSITION COMPRISING PYRIMETHANIL AND IPRODIONE BAYER CROPSCIENCE S.A. (FR) 2003-03-27 WO disclosed