Metalaxyl

Metalaxyl

SCHEMBL5075392

COCC(=O)N(c1c(C)cccc1C)C(C)C(=O)OC.[Cu]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.56
MEN1 O00255 5/20 0.56
NPSR1 Q6W5P4 2/20 0.56
PLA2G1B P04054 1/20 0.56
HTT P42858 1/20 0.56
ATG4B Q9Y4P1 1/20 0.56
RORC P51449 1/20 0.43
NLRP3 Q96P20 5/20 0.38
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.36
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metalaxyl SCHEMBL245477 0.99 KMT2A (0.55) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL8852635 0.99 KMT2A (0.55) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL20990 0.99 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL55820 0.99 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL8376541 0.99 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL8817105 0.99 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL30058456 0.99 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Mefenoxam SCHEMBL22529 0.99 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL5070290 0.99 KMT2A (0.58) KMT2AMEN1NPSR1PLA2G1BHTT
Metalaxyl SCHEMBL156622 0.97 KMT2A (0.56) KMT2AMEN1NPSR1PLA2G1BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323188-B2 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2008-01-29 US disclosed
US-7001605-B2 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-02-21 US disclosed
US-20050255171-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. 2005-11-17 US disclosed
EP-0979034-B1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA (JP) 2003-02-26 EP disclosed
US-20020142021-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. 2002-10-03 US disclosed
US-6375965-B1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-04-23 US disclosed
EP-0979034-A1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-02-16 EP disclosed
WO-1998048628-A1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 1998-11-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050255171-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same IPMK, PPA1, ERG28 KMT2A 4046/4885MEN1 302/4885NPSR1 3238/4885
US-20020142021-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same PPA1, IPMK, ERG28 KMT2A 4153/4885MEN1 261/4885NPSR1 3378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.