Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990806 | 0.78 | CYP2D6 (0.35) | CYP2D6CYP2C19 | |
| SCHEMBL4540745 | 0.77 | CYP2D6 (0.39) | MEN1GAAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL4885972 | 0.70 | CYP2D6 (0.38) | MEN1GAAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL22076985 | 0.68 | CYP2D6 (0.37) | MEN1GAAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL2556795 | 0.68 | CYP2D6 (0.37) | MEN1GAAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL838330 | 0.68 | CYP2D6 (0.37) | MEN1GAAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL21877077 | 0.67 | CYP2D6 (0.39) | MEN1GAAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL1518694 | 0.67 | — | — | |
| SCHEMBL2880343 | 0.67 | CYP2D6 (0.33) | MEN1GAAKMT2ACYP2D6CYP2C19 | |
| SCHEMBL3323698 | 0.66 | CYP2D6 (0.43) | MEN1GAAKMT2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008540768-A | — | — | 2008-11-20 | — | — | JP | claimed |
| EP-1879958-A1 | CROSSLINKED POLYETHYLENE COMPOSITIONS | Momentive Performance Materials Inc. (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006124368-A1 | CROSSLINKED POLYETHYLENE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2006-11-23 | — | — | WO | claimed |
| EP-1021486-B1 | SILANE VULCANIZED THERMOPLASTIC ELASTOMERS | GEN ELECTRIC (US) | 2004-09-22 | — | — | EP | disclosed |