SCHEMBL28990806

SCHEMBL28990806

CO[Si](OC)(OC)C(CCNC(=O)O)[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
HPGD P15428 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4540745 0.82 CYP2D6 (0.39) CYP2D6CYP2C19MTNR1AMTNR1BALDH1A1
SCHEMBL9722592 0.82 MTNR1A (0.33) MTNR1AMTNR1B
SCHEMBL5070299 0.78 MEN1 (0.33) CYP2D6CYP2C19
SCHEMBL21877077 0.72 CYP2D6 (0.39) CYP2D6CYP2C19MTNR1AMTNR1BALDH1A1
SCHEMBL3256673 0.71 CYP2D6 (0.43) CYP2D6CYP2C19MTNR1AMTNR1BHPGD
SCHEMBL3323698 0.71 CYP2D6 (0.43) CYP2D6CYP2C19MTNR1AMTNR1BHPGD
SCHEMBL8982322 0.71 CYP2D6 (0.43) CYP2D6CYP2C19MTNR1AMTNR1BHPGD
SCHEMBL20954114 0.70 CYP2D6 (0.36) CYP2D6CYP2C19
SCHEMBL9067196 0.69 TSHR (0.43) ALDH1A1
SCHEMBL667964 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114344017-B Medical bill and preparation method thereof 中昊晨光化工研究院有限公司 2023-04-28 CN claimed