SCHEMBL5070717

SCHEMBL5070717

C[C@@]1(n2ccc(N)nc2=O)O[C@H](CO)[C@@H](O)C1(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3A Q14432 3/20 0.47
PDE4D Q08499 1/20 0.47
SLC29A1 Q99808 1/20 0.47
LMNA P02545 5/20 0.47
MTOR P42345 2/20 0.47
THRB P10828 1/20 0.47
MDM2 Q00987 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
CACNA1F O60840 2/20 0.38
ALB P02768 2/20 0.38
MAPT P10636 2/20 0.38
CACNA1D Q01668 2/20 0.38
CACNA1S Q13698 2/20 0.38
CACNA1C Q13936 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
NT5E P21589 1/20 0.33
POLA1 P09884 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL872890 0.90 PDE3A (0.47) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL1880455 0.89 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL28997179 0.85 PDE3A (0.52) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL18740735 0.85 PDE3A (0.45) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL28780917 0.84 PDE3A (0.45) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL27999217 0.82 PDE3A (0.52) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL4248207 0.81 PDE3A (0.40) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL3474446 0.81 PDE3A (0.53) PDE3APDE4DSLC29A1LMNAMTOR
Hydrochloric Acid SCHEMBL3345909 0.80 PDE3A (0.52) PDE3APDE4DSLC29A1LMNAMTOR
Methyl Alcohol SCHEMBL27751480 0.80 PDE3A (0.52) PDE3APDE4DSLC29A1LMNAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634200-A1 ENZYMATIC SYNTHESIS OF NTP AND NQP Codexis, Inc. (US) 2025-10-22 EP disclosed
WO-2024129235-A1 ENZYMATIC SYNTHESIS OF NTP AND NQP CODEXIS, INC. (US) 2024-06-20 WO disclosed
WO-2023230207-A1 FLUOROGENIC NUCLEOSIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-11-30 WO disclosed
EP-1871883-A1 PROCESS FOR THE PRODUCTION OF FINE CHEMICALS Metanomics GmbH (DE) 2008-01-02 EP disclosed
WO-2006092449-A2 PROCESS FOR THE PRODUCTION OF FINE CHEMICALS METANOMICS GMBH (DE) 2006-09-08 WO disclosed