SCHEMBL872890

SCHEMBL872890

C[C@@]1(n2ccc(N)nc2=O)O[C@H](CO)[C@@H](O)[C@@]1(C)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3A Q14432 3/20 0.47
PDE4D Q08499 1/20 0.47
SLC29A1 Q99808 1/20 0.47
LMNA P02545 5/20 0.47
MTOR P42345 2/20 0.47
THRB P10828 1/20 0.47
MDM2 Q00987 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
CACNA1F O60840 2/20 0.38
ALB P02768 2/20 0.38
MAPT P10636 2/20 0.38
CACNA1D Q01668 2/20 0.38
CACNA1S Q13698 2/20 0.38
CACNA1C Q13936 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 2/20 0.37
ALDH1A1 P00352 2/20 0.37
DNMT1 P26358 2/20 0.33
NT5E P21589 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5070717 0.90 PDE3A (0.47) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL1880455 0.89 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL27999217 0.87 PDE3A (0.52) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL18740735 0.85 PDE3A (0.45) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL28780917 0.84 PDE3A (0.45) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL13454615 0.83 PDE3A (0.43) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL13454621 0.83 PDE3A (0.43) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL13454641 0.83 PDE3A (0.46) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL4248207 0.81 PDE3A (0.40) PDE3APDE4DSLC29A1LMNAMTOR
SCHEMBL18740733 0.81 PDE3A (0.40) PDE3APDE4DSLC29A1LMNAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141676-A1 THERAPEUTIC mRNA THE UNIVERSITY OF MELBOURNE (AU) 2023-08-03 WO claimed
EP-0948256-A4 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA UNIV WASHINGTON (US) 2007-10-24 EP claimed
US-6887707-B2 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA UNIVERSITY OF WASHINGTON (US) 2005-05-03 US claimed
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-06-26 US claimed
WO-2001085220-A1 LABELED NUCLEOSIDES AND METHOD FOR THEIR PREPARATION RNA-TEC N.V. (BE) 2001-11-15 WO claimed
JP-2001513568-A 2001-09-04 JP claimed
EP-1011688-A1 USE OF URIDINE 5'-DIPHOSPHATE AND ANALOGS THEREOF FOR THE TREATMENT OF LUNG DISEASES The University of North Carolina at Chapel Hill (US) 2000-06-28 EP claimed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP claimed
WO-1999009998-A1 USE OF URIDINE 5'-DIPHOSPHATE AND ANALOGS THEREOF FOR THE TREATMENT OF LUNG DISEASES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1999-03-04 WO claimed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO claimed
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2026-04-07 US disclosed
WO-2024151687-A1 GENETIC SWITCHES AND THEIR USE IN TREATING CANCER FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-07-18 WO disclosed
WO-2024151685-A1 RECOMBINANT NUCLEIC ACID MOLECULES AND THEIR USE IN WOUND HEALING BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2024-07-18 WO disclosed
WO-2024151673-A2 RECOMBINANT NUCLEIC ACID MOLECULES AND THEIR USE IN WOUND HEALING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
EP-4396349-A1 COMPOSITIONS AND METHODS FOR MODULATING NLRP3 OR NLRP1 EXPRESSION Molecular Axiom, LLC (US) 2024-07-10 EP disclosed
EP-0948256-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1999-10-13 EP disclosed
WO-1999009998-A1 USE OF URIDINE 5'-DIPHOSPHATE AND ANALOGS THEREOF FOR THE TREATMENT OF LUNG DISEASES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1999-03-04 WO disclosed
WO-1998018324-A1 INDUCTION OF VIRAL MUTATION BY INCORPORATION OF MISCODING RIBONUCLEOSIDE ANALOGS INTO VIRAL RNA THE UNIVERSITY OF WASHINGTON (US) 1998-05-07 WO disclosed
EP-0829104-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1998-03-18 EP disclosed
WO-1996035239-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030119764-A1 Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA SAMHD1, BCDIN3D, DCTD PDE3A 3818/4885PDE4D 1220/4885SLC29A1 304/4885
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents LNPK, PCTP, PLTP PDE3A 3615/4885PDE4D 3735/4885SLC29A1 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.