SCHEMBL5070959

SCHEMBL5070959

C=CC(=O)Oc1cccc(Br)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
CYP1A2 P05177 2/20 0.50
MAPT P10636 2/20 0.50
GAA P10253 1/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 5/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
CYP2C19 P33261 1/20 0.49
TGM2 P21980 1/20 0.49
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.42
THRB P10828 2/20 0.41
MAOB P27338 3/20 0.41
HSD17B3 P37058 1/20 0.41
PARP1 P09874 1/20 0.40
NCEH1 Q6PIU2 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL421454 0.86 KMT2A (0.56) KMT2AMAPTALDH1A1TGM2KDM4E
SCHEMBL14173221 0.81 KMT2A (0.50) KMT2AMAPTGAAALDH1A1TGM2
SCHEMBL6406233 0.81 KMT2A (0.56) KMT2ACYP1A2MAPTGAARECQL
SCHEMBL379254 0.81 MEN1 (0.45) KMT2AMEN1THRB
SCHEMBL8579809 0.80 KMT2A (0.59) KMT2ACYP1A2MAPTGAARECQL
SCHEMBL29861297 0.79 CYP3A4 (0.61) KMT2AALDH1A1MEN1LMNATHRB
SCHEMBL220089 0.79 CYP3A4 (0.61) KMT2AALDH1A1MEN1LMNATHRB
SCHEMBL17350484 0.79 KMT2A (0.48) KMT2ACYP1A2MAPTGAARECQL
SCHEMBL8759992 0.79 CYP1A2 (0.51) KMT2ACYP1A2MAPTGAARECQL
SCHEMBL28663421 0.79 NCEH1 (0.57) KMT2ACYP1A2MAPTALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4479101-B1 PHOTOPOLYMERISABLE COMPOSITION FOR ADHESIVE FOR BIOLOGICAL TISSUE COHESIVES (FR) 2026-03-04 EP claimed
US-20250170299-A1 SURGICAL ADHESIVES COHESIVES (FR) 2025-05-29 US claimed
US-20250152772-A1 PHOTOPOLYMERISABLE COMPOSITION FOR ADHESIVE FOR BIOLOGICAL TISSUES COHESIVES (FR) 2025-05-15 US claimed
US-12239759-B2 Surgical adhesives COHESIVES (FR) 2025-03-04 US claimed
EP-4479101-A1 PHOTOPOLYMERISABLE COMPOSITION FOR ADHESIVE FOR BIOLOGICAL TISSUE Cohesives (FR) 2024-12-25 EP claimed
WO-2023156749-A1 PHOTOPOLYMERISABLE COMPOSITION FOR ADHESIVE FOR BIOLOGICAL TISSUE COHESIVES (FR) 2023-08-24 WO claimed
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2022-07-28 US claimed
US-20220143264-A1 SURGICAL ADHESIVES COHESIVES (FR) 2022-05-12 US claimed
US-11207443-B2 Surgical adhesives COHESIVES (FR) 2021-12-28 US claimed
US-20180280564-A1 SURGICAL ADHESIVES COHESIVES (FR) 2018-10-04 US claimed
EP-1015505-B1 PRODUCTION OF PHOTOPOLYMERIZED POLYESTER HIGH INDEX OPHTHALMIC LENSES SIGNET ARMORLITE INC (US) 2005-03-09 EP claimed
EP-0783710-B1 POLYESTER RESIN-BASED HIGH INDEX OPHTHALMIC LENSES HAVING IMPROVED OPTICAL UNIFORMITY AND/OR TINTABILITY SIGNET ARMORLITE INC (US) 2002-05-29 EP claimed
US-6099123-A A CROSSLINKABLE CASTING POLYMERIC MATERIAL CONSISTS OF AN UNSATURATED POLYESTER, A CROSSLINKING AGENT AND A PHOTOINITIATORS SIGNET ARMORLITE, INC. (US) 2000-08-08 US claimed
EP-1015505-A1 PRODUCTION OF PHOTOPOLYMERIZED POLYESTER HIGH INDEX OPHTHALMIC LENSES SIGNET ARMORLITE, INC. (US) 2000-07-05 EP claimed
US-5886764-A UNSATURATED POLYESTER RESIN, AN ADDITIVE SELECTED FROM THE GROUP CONSISTING OF ABOUT 1% TO ABOUT 20% BY WEIGHT OF AN ALLYLIC ESTER MONOMER, ABOUT 1% TO ABOUT 20% BY WEIGHT OF AN ACRYLATE, AND MIXTURES THEREOF, AND AN EXOTHERM DEPRESSANT SIGNET ARMORLITE, INC. (US) 1999-03-23 US claimed
WO-1999011682-A1 PRODUCTION OF PHOTOPOLYMERIZED POLYESTER HIGH INDEX OPHTHALMIC LENSES SIGNET ARMORLITE, INC. (US) 1999-03-11 WO claimed
US-5852112-A Polyester resin-based high index ophthalmic lenses having improved optical unformity and/or tintability SIGNET ARMORLITE, INC. (US) 1998-12-22 US claimed
US-5694195-A Polyester resin-based high index ophthalmic lenses having improved optical uniformity and/or tintability SIGNET ARMORLITE, INC. (US) 1997-12-02 US claimed
US-20250170299-A1 SURGICAL ADHESIVES COHESIVES (FR) 2025-05-29 US disclosed
WO-1996010760-A1 POLYESTER RESIN-BASED HIGH INDEX OPHTHALMIC LENSES HAVING IMPROVED OPTICAL UNIFORMITY AND/OR TINTABILITY SIGNET ARMORLITE, INC. (US) 1996-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES ACACB, ACACA, FABP7 KMT2A 1056/4885CYP1A2 3155/4885MAPT 724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.