SCHEMBL507208

SCHEMBL507208

Clc1ccc(N=C=Nc2ccc(Cl)c(Cl)c2)cc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.68
TDP1 Q9NUW8 1/20 0.68
HTR3E A5X5Y0 2/20 0.50
HTR3B O95264 2/20 0.50
HTR3A P46098 2/20 0.50
HTR3D Q70Z44 2/20 0.50
HTR3C Q8WXA8 2/20 0.50
KMT2A Q03164 1/20 0.45
ITGB3 P05106 1/20 0.44
ITGAV P06756 1/20 0.44
AHR P35869 5/20 0.42
TP53 P04637 1/20 0.42
PMM2 O15305 1/20 0.40
MPI P34949 1/20 0.40
TSHR P16473 3/20 0.39
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31044049 1.00 MAPK1 (0.68) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL9129351 0.81 MAPK1 (0.62) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL8759349 0.81 MAPK1 (0.62) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL31576798 0.81 MAPK1 (0.62) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL29375842 0.81 MAPK1 (0.62) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL31347853 0.81 MAPK1 (0.63) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL58874 0.81 MAPK1 (1.00) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL26675676 0.81 MAPK1 (0.63) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL29976261 0.81 TDP1 (0.63) MAPK1TDP1HTR3EHTR3BHTR3A
SCHEMBL29376406 0.81 MAPK1 (1.00) MAPK1TDP1HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024143405-A1 METHOD FOR PRODUCING RESIN FOR RECYCLING 花王株式会社 2024-07-04 WO disclosed
CN-116234846-B Resin composition and molded article 株式会社可乐丽 2024-07-02 CN disclosed
CN-113574104-B Method for improving tracking resistance of thermoplastic resin 宝理塑料株式会社 2024-06-18 CN disclosed
WO-2024111181-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT ポリプラ・エボニック株式会社 2024-05-30 WO disclosed
CN-115427515-B Resin composition for galvanometer type laser welding, molded article, set for galvanometer type laser welding, in-vehicle camera component, in-vehicle camera module, ultraviolet exposure body, and method for producing molded article 三菱化学株式会社 2024-05-24 CN disclosed
WO-2024101133-A1 FLAME RETARDANT POLYESTER ELASTOMER RESIN COMPOSITION 東洋紡エムシー株式会社 2024-05-16 WO disclosed
CN-118019791-A Thermoplastic polymer composition with enhanced tracking resistance and polymer articles made therefrom 国际人造丝公司 2024-05-10 CN disclosed
CN-115135720-B Polyester elastomer resin composition 东洋纺MC株式会社 2024-04-23 CN disclosed
EP-4352150-A1 THERMOPLASTIC POLYMER COMPOSITION WITH INCREASED ELECTRICAL TRACKING RESISTANCE AND POLYMER ARTICLES MADE THEREFROM Celanese International Corporation (US) 2024-04-17 EP disclosed
EP-3967724-B1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2024-02-28 EP disclosed
EP-1792941-A1 RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2007-06-06 EP disclosed
US-20060079638-A1 Polybutylene terephthalate resin composition WINTECH POLYMER LTD. (JP) 2006-04-13 US disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed
US-5866672-A HALOGEN FLAME RETARDANT, EPOXY COMPOUNDS OR CARBODIIMIDE COMPOUNDS AND AN ANTIMONY COMPOUND KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-02-02 US disclosed
EP-0763567-A1 FLAME-RETARDANT POLYETHYLENE TEREPHTHALATE RESIN COMPOSITIONS Kanegafuchi Kagaku Kogyo Kabushiki Kaisha (JP) 1997-03-19 EP disclosed
EP-0027197-B1 PROCESS FOR THE PRODUCTION OF ADDITION COMPOUNDS FROM CARBODIIMIDES AND COMPOUNDS CONTAINING HYDROXYL GROUPS BAYER AG (DE) 1982-08-25 EP disclosed
US-4321394-A Process for the production of addition compounds of carbodiimides and compounds containing hydroxyl groups BAYER AKTIENGESELLSCHAFT (DE) 1982-03-23 US disclosed
EP-0027197-A1 Process for the production of addition compounds from carbodiimides and compounds containing hydroxyl groups BAYER AG (DE) 1981-04-22 EP disclosed
US-3975329-A HYDROLYTIC AND THERMAL STABILITY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 US disclosed