SCHEMBL58874

SCHEMBL58874

O=C=Nc1ccc(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
CYP3A4 P08684 3/20 0.48
TRPA1 O75762 1/20 0.48
HTR3E A5X5Y0 2/20 0.47
HTR3B O95264 2/20 0.47
HTR3A P46098 2/20 0.47
HTR3D Q70Z44 2/20 0.47
HTR3C Q8WXA8 2/20 0.47
TSHR P16473 4/20 0.45
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGAV P06756 1/20 0.41
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
AHR P35869 2/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376406 1.00 MAPK1 (1.00) MAPK1TDP1CYP3A4TRPA1HTR3E
SCHEMBL7981297 0.94 MAPK1 (0.88) MAPK1TDP1CYP3A4TRPA1HTR3E
Dimethylamine SCHEMBL11830270 0.92 MAPK1 (0.85) MAPK1TDP1CYP3A4TRPA1HTR3E
SCHEMBL8942897 0.87 TDP1 (0.76) MAPK1TDP1CYP3A4TRPA1HTR3E
O-Xylene SCHEMBL27865799 0.87 MAPK1 (0.76) MAPK1TDP1CYP3A4TRPA1HTR3E
SCHEMBL8594415 0.87 TDP1 (0.76) MAPK1TDP1CYP3A4TRPA1HTR3E
Toluene SCHEMBL27882172 0.86 MAPK1 (0.73) MAPK1TDP1CYP3A4TRPA1HTR3E
SCHEMBL2770967 0.84 MAPK1 (0.73) MAPK1TDP1CYP3A4TRPA1HTR3E
SCHEMBL29365125 0.83 TDP1 (0.70) MAPK1TDP1CYP3A4TRPA1HTR3E
SCHEMBL29709073 0.83 TDP1 (0.70) MAPK1TDP1CYP3A4TRPA1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350191-A Production process of diuron technical 安徽广信农化股份有限公司 2025-01-24 CN claimed
CN-115960017-B Modified acrylic ester monomer and photo-curable resin thereof 上海华峰龙湾技术有限公司 2024-11-22 CN claimed
CN-118530448-A Synthesis process of diuron 安徽广信农化股份有限公司 2024-08-23 CN claimed
CN-118204067-A Lithium adsorbent, preparation method and application 广东邦普循环科技有限公司 2024-06-18 CN claimed
CN-118084739-A Continuous preparation method and device of diuron 江苏快达农化股份有限公司 2024-05-28 CN claimed
US-20240154124-A1 NEGATIVE ELECTRODE PLATE AND LITHIUM-ION BATTERY COMPRISING SAME ZHUHAI COSMX BATTERY CO., LTD. (CN) 2024-05-09 US claimed
CN-117964892-A Modified macromer, preparation method thereof and application thereof in polymer polyol 中国石油化工股份有限公司 2024-05-03 CN claimed
CN-117327201-A Hydrophobic nanocellulose and preparation method and application thereof 中国科学院理化技术研究所 2024-01-02 CN claimed
CN-116768764-A Process for preparing urea derivatives 安道麦阿甘有限公司 2023-09-19 CN claimed
CN-116525948-A Method for inhibiting corrosion of aluminum foil of lithium battery current collector based on isocyanate additive 临沂大学 2023-08-01 CN claimed
CN-101187078-A Preparation method of carbon nanometer tube/ polyimide composite fiber UNIV DONGHUA (CN) 2008-05-28 CN claimed
CN-101177527-A Method for preparing carbon nano-tube/polyimide composite material UNIV DONGHUA (CN) 2008-05-14 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
WO-2004078768-A2 ISOCYANATE ADDUCTS ALBEMARLE CHEMICALS UK LIMITED (GB) 2004-09-16 WO claimed
EP-0513541-B1 Process for the preparation of iodoalkynyl carbamates MITSUI TOATSU CHEMICALS (JP) 1995-12-20 EP claimed
US-5229243-A Addition polymer core, polyurethane or polythiourethane shell KAO CORPORATION (JP) 1993-07-20 US claimed
US-5183927-A PROCESS FOR THE PREPARATION OF IODOALKYNYL CARBAMATES MITSUI TOATSU CHEMICALS INCORPORATED (JP) 1993-02-02 US claimed
EP-0513541-A2 Process for the preparation of iodoalkynyl carbamates MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-11-19 EP claimed
US-5103044-A One step crystallizing from dissolving with chlorotoluene and chlorobenzene I.PI.CI. S.P.A. (IT) 1992-04-07 US claimed
US-3976610-A Acrylate rubber vulcanizable compositions THE B. F. GOODRICH COMPANY (US) 1976-08-24 US claimed