SCHEMBL5072255

SCHEMBL5072255

CC(C)CCOc1cc(-c2ccccc2)c(-c2cc(CCl)ccc2CCl)cc1OCCC(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.37
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
TLR8 Q9NR97 1/20 0.36
SIGMAR1 Q99720 4/20 0.35
HTT P42858 1/20 0.35
MGAM O43451 2/20 0.34
GAA P10253 2/20 0.34
SI P14410 2/20 0.34
MGAM2 Q2M2H8 2/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
S1PR1 P21453 1/20 0.33
S1PR5 Q9H228 1/20 0.33
TTR P02766 1/20 0.33
ADRB2 P07550 1/20 0.33
HTR7 P34969 1/20 0.32
BRS3 P32247 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5073906 0.84 IDO1 (0.40) IDO1PPARGPPARDPPARATLR8
SCHEMBL5074517 0.78 HTT (0.41) IDO1PPARGPPARDPPARAHTT
SCHEMBL4345051 0.74 CSNK2A1 (0.42) TTR
SCHEMBL7097664 0.72 GCGR (0.41) PPARGTLR8GAATP53MAPT
SCHEMBL1446870 0.71 TDP1 (0.42) PPARGPPARDPPARAMGAMGAA
SCHEMBL2784719 0.70 ALOX5 (0.40) PPARGPPARDPPARAS1PR1S1PR5
SCHEMBL10650264 0.70 HTT (0.51) IDO1TLR8HTTTP53MAPT
SCHEMBL6228875 0.70 TDP1 (0.37) IDO1PPARGPPARDPPARATLR8
SCHEMBL6860303 0.69 TDP1 (0.36) IDO1TLR8HTTTP53MAPT
SCHEMBL4337116 0.69 MAPT (0.40) HTTGAATP53MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377570-B2 Poly(arylenevinylene) and poly(heteroarylenevinylene) light emitting polymer and polymer light-emitting devices AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-02-19 US disclosed
EP-1812493-A4 POLY(ARYLENEVINYLENE) AND POLY(HETEROARYLENEVINYLENE) LIGHT EMITTING POLYMERS AND POLYMER LIGHT-EMITTING DEVICES AGENCY SCIENCE TECH & RES (SG) 2008-12-31 EP disclosed
US-20080272691-A1 Poly(Arylenevinylene) and Poly(Heteroarylenevinylene) Light Emitting Polymers and Polymer Light-Emitting Devices AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-11-06 US disclosed
EP-1812493-A1 POLY(ARYLENEVINYLENE) AND POLY(HETEROARYLENEVINYLENE) LIGHT EMITTING POLYMERS AND POLYMER LIGHT-EMITTING DEVICES Agency for Science, Technology and Research (SG) 2007-08-01 EP disclosed
WO-2006049579-A1 POLY(ARYLENEVINYLENE) AND POLY(HETEROARYLENEVINYLENE) LIGHT EMITTING POLYMERS AND POLYMER LIGHT-EMITTING DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-05-11 WO disclosed