SCHEMBL5072271

SCHEMBL5072271

C=C(C)C(=O)OCCC(=O)OCCOCCOC(=O)CCOC(=O)C(=C)C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.63
TSHR P16473 6/20 0.47
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
DGKA P23743 1/20 0.38
ALDH1A1 P00352 5/20 0.38
TP53 P04637 2/20 0.36
HIF1A Q16665 2/20 0.36
ADRA2A P08913 1/20 0.36
ADRA1A P35348 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28959481 0.94 THRB (0.66) THRBTSHRTDP1POLBAPEX1
SCHEMBL2466488 0.94 THRB (0.59) THRBTSHRTDP1POLBAPEX1
SCHEMBL27674984 0.91 THRB (0.61) THRBTSHRTDP1POLBAPEX1
SCHEMBL8492855 0.89 THRB (0.65) THRBTSHRTDP1POLBAPEX1
SCHEMBL16744077 0.88 THRB (0.61) THRBTSHRTDP1POLBAPEX1
SCHEMBL124287 0.88 THRB (0.61) THRBTSHRTDP1POLBAPEX1
SCHEMBL700642 0.88 THRB (0.79) THRBTSHRTDP1POLBAPEX1
SCHEMBL2367616 0.88 THRB (0.79) THRBTSHRTDP1POLBAPEX1
SCHEMBL672102 0.88 THRB (0.79) THRBTSHRTDP1POLBAPEX1
SCHEMBL22166147 0.88 THRB (0.79) THRBTSHRTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080193722-A1 Hard coat film TOPPAN PRINTING CO., LTD. (JP) 2008-08-14 US disclosed
EP-0604677-B1 Method of making coated shaped articles MITSUBISHI RAYON CO (JP) 1999-08-11 EP disclosed
US-5470616-A Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1995-11-28 US disclosed
EP-0604677-A1 Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1994-07-06 EP disclosed